Chapter 15  The Chromosomal Basis of Inheritance

Table of Contents

The Chromosomal Theory of Inheritance, 1902

Evidence of Mendel’s Factors

Drosophila experiment

Drosophila experiment, cont.

Drosophila experiment, cont.

Linked Genes

Linked Genes, cont. 

Unlinked Genes

Linked and Unlinked Genes

Crossing Over

Crossing Over, cont.

Human Genetics

Amniocentesis Chorionic villi sampling

Human Genome

Aneuploidy

Monosomics

Trisomics 

Autosomic Aneuploidies

Down Syndrome

Incidence of Down Syndrome

Down Syndrome Types

Trisomy 21

Translocation

Mosaic Trisomy 21

21st Chromosome

Cause of Down Syndrome

Hypotheses

Sex Chromosomal Aneuploidies

Y Chromosome

X Chromosome

Lyon Hypothesis

Barr Bodies

XX Nondisjunction spermatogenesis and oogenesis

XXX

XXY (XXYY, XXXY, XXXXY, XXXXXY)

YO

XO

YY Nondisjunction spermatogenesis

Pedigree

trait present trait absent male female

trait present trait absent

Multiple Alleles

ABO blood groups 

Rh factor

Genetic Disorders

Genetic Disorders list

Cystic fibrosis (CF)

Sickle-cell disease (homozygous) Sickle-cell trait (heterozygous)

Tay-Sachs disease

Tay-Sachs disease, cont.

Phenylketonuria (PKU)

Hemophilia

Huntington’s disease

Hypercholesterolemia

Genomic Imprinting

Chapter 14

Email: dcardenas@ccccd.edu

Home Page: http://jade.ccccd.edu/BIOPAGE/faculty/cardenas/~cardenas.html 

Best experienced with

Click here to start. 

Download presentation source